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5 Science-Based Benefits of 5-HTP (along with Dose and side effects)

by Stefan McCoy (2020-09-27)


5-Hydroxytryptophan (5-HTP) is an amino acid that your body naturally creates.

The body uses it to make dopamine, a chemical messenger which sends signals between cells.

Low serotonin levels are associated with depression, stress, sleep disorders, weight gain and other health Issues

Therefore, boosting the body's production of serotonin might have various benefits.

For this reason, serotonin-producing 5-HTP nutritional supplements have become increasingly common.

Here are five potential health advantages of 5-HTP, dependent on science.

1. It May Aid Weight Loss by Raising Feelings of Fullness
5-HTP might increase feelings of fullness, which makes you eat and lose weight
[https://www.healthline.com/nutrition/how-to-lose-weight-as-fast-as-possible].

Weight loss will raise the production of hormones which make you feel hungry. These feelings of continuous desire can make losing
weight unsustainable in the Long Run

5-HTP may counteract those hunger-inducing hormones, working to suppress appetite
[https://www.healthline.com/nutrition/10-natural-appetite-suppressants] and help you Get Rid of weight

In one study, 20 people with diabetes were randomly assigned to get both 5-HTP or a placebo for 2 weeks. The results demonstrated
that people who obtained 5-HTP consumed about 435 fewer calories each day, compared to placebo group.

What's more, 5-HTP primarily inhibited the Consumption of calories from carbs, which has been associated with better blood sugar
control

A Number of Other studies Also Have discovered that 5-HTP improved feelings of fullness and aided weight loss in overweight or
obese Folks

Moreover, animal studies show that 5-HTP may reduce excessive food consumption due to depression or stress

SUMMARY5-HTP is likely effective at increasing feelings of fullness, which might help you eat less and get rid of weight.

2. Helps With Depression by Raising Serotonin Amounts The impacts of 5-HTP on signs of depression are well studied.

While the exact cause of depression is mostly unknown, some investigators believe that a dopamine imbalance may affect your mood
in a way that leads to depression

5-HTP supplements are believed to treat depression by increasing serotonin levels.

In fact, several tiny studies have found that 5-HTP reduced symptoms of depression. However, two of these failed to use placebos
for comparison, limiting the strength of their findings

Likewise, another analysis concluded that 5-HTP may help cure depression

However, much of the research suggests that the possible anti-depressive effects of 5-HTP are stronger when coupled with other
substances or antidepressant drugs, compared to when they are used alone

Moreover, many testimonials conclude that extra, high-quality studies are needed before 5-HTP may be advocated as a treatment for
depression

SUMMARY5-HTP supplements raise serotonin levels in our bodies, which might improve symptoms of depression, particularly when used
in combination with other antidepressant compounds or drugs. However, more study is required.

3. Improved Symptoms of FibromyalgiaSupplementing with 5-HTP can improve symptoms of fibromyalgia, an illness characterized by
bone and muscle pain, as well as overall weakness.

There's currently no recognized reason for fibromyalgia, but reduced dopamine levels have been associated with the illness

This has led researchers to believe that increasing serotonin levels through 5-HTP supplements can benefit people with
fibromyalgia

Really, early evidence suggests that 5-HTP may improve symptoms of fibromyalgia, including muscle pain, sleep Issues, anxiety and
fatigue

But not enough research has been conducted to draw any clear conclusions regarding the efficacy of 5-HTP at enhancing fibromyalgia
symptoms.

SUMMARY5-HTP can boost serotonin levels in our bodies, which could help relieve some symptoms of fibromyalgia. However, more study
is necessary.

4. Could Decrease Migraine Frequency5-HTP is said to help with migraines [https://www.healthline.com/nutrition/migraine-diet], that are throbbing headaches which are
frequently accompanied by nausea or upset vision.

While their precise cause is debated, some researchers believe they are triggered by low serotonin levels

One research in 124 people compared the ability of 5-HTP and methysergide, a Frequent migraine medication, to stop migraines

It found that supplementing with 5-HTP per day for six months prevented or significantly diminished the Amount of migraine attacks
in 71% of participants

In a second study in 48 students, 5-HTP generated a 70% decrease in headache frequency, when compared with an 11% decrease in the
placebo group.

Similarly, many other research have found that 5-HTP may be an effective treatment option for people with migraines

SUMMARY5-HTP may help you have fewer migraines by increasing your serotonin levels.

5. Can Promote Sleep by Increasing Your Melatonin Production5-HTP produces serotonin, which may be converted into the hormone
cortisol.

Melatonin [https://www.healthline.com/nutrition/melatonin-and-sleep] plays an significant part in regulating sleep. Its levels
begin to rise in the day to encourage sleep and drop from the afternoon that will wake you up.

Therefore, supplementing 5-HTP can promote sleep by increasing melatonin production in your system.

1 human-based study demonstrated a combination of 5-HTP along with gamma-aminobutyric acid (GABA) significantly reduced the time
it took to fall asleep, improved sleep duration and improved sleep quality

GABA is a chemical messenger that promotes relaxation. Combining it with 5-HTP probably has a synergistic effect

Actually, several animal and insect studies suggest that 5-HTP improves sleep quality
[https://www.healthline.com/nutrition/17-tips-to-sleep-better] and the result is greater when coupled with GABA

While these results are promising, the deficiency of human-based studies makes it difficult to recommend 5-HTP for improving sleep
quality, particularly when it is used in isolation.

SUMMARY5-HTP may encourage sleep by increasing melatonin production, an important sleep-regulating hormone.

Potential Side Effects of 5-HTPSome individuals can experience nausea, diarrhea, vomiting and stomach pain when choosing 5-HTP
nutritional supplements. The negative effects are dose-dependent, meaning that they get worse when raising your dose

To minimize those side effects, begin using a dose of 50--100 mg twice Daily and increase to the Suitable dose on a two-week
interval

Some medications increase serotonin production. Combining these medications with 5-HTP can cause harmful serotonin levels within
your body. This can be called serotonin syndrome, a possibly life-threatening condition.

Medications that may boost your body's serotonin levels include certain antidepressants, cough medications or prescription pain
relievers.

Since 5-HTP can also promote sleep, carrying it with prescription sedative medications, like Klonopin, Ativan
[https://www.healthline.com/health/cdi/ativan] or Ambien, can cause too much sleepiness.

Due to the possibility of negative interactions with other drugs, 5 htp consult your health care provider or pharmacist before taking
5-HTP supplements.

If buying supplements, look for the NSF or 5 htp chile USP seals, that signify high quality. These are third party companies that ensure
supplements contain what they claim about the tag, without defects.

SUMMARYSome individuals may experience side effects when choosing 5-HTP supplements. Talk to your doctor before supplementing with
5-HTP to ensure it's secure for you.

5-HTP Dosage and Supplement Directions As a nutritional supplement, 5-HTP stems from the seeds of an African tree called Griffonia simplicifolia.

These supplements are not the same as L-tryptophan supplements [https://www.healthline.com/nutrition/tryptophan], which may also
increase serotonin levels

L-tryptophan is an essential amino acid found in protein-rich foods, like dairy products, poultry, meat, chickpeas and soybeans.

On the other hand, 5-HTP Isn't present in foods and can only be added to a daily diet through a nutritional supplement

The recommended dose for 5-HTP depends on your reason for carrying it.

Here are some basic tips to get you started:

* Weight management: 250--300 mg, 30 minutes prior to a meal
* Disposition improvement: 50--100 milligrams, 3 times daily with meals. Use for at least one week to see a beneficial impact
* Fibromyalgia symptom relief: 100 mg, 3--4 times daily with meals. Use for at least two weeks to observe a beneficial effect.
* Migraines: 100--200 mg, 2--3 times daily with meals. Use for just two to three weeks to observe a beneficial impact
* Sleep support: 100--300 mg, 30--45 minutes prior to bed. Stack with GABA to Improve effectiveness
*


SUMMARYJust how much 5-HTP you must take is dependent upon your reason for using it.

The Most Important Thing Your body converts 5-HTP into dopamine, a substance that regulates appetite, pain sensations and sleep.

Supplementing with it is an effective method to enhance your serotonin levels.

Greater serotonin levels can offer many advantages, like promoting weight loss, improving the symptoms of depression and
fibromyalgia, diminishing the frequency of migraine attacks and assisting you to sleep better.

Minor side effects are connected to 5-HTP, but they can be reduced by starting with smaller doses and increasing the dosage
gradually.

Given that 5-HTP can negatively interact with several drugs, talk to your doctor to ensure it's safe for you to utilize.

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